Technology

Bristol secures £45M to advance gene therapy treatment of chronic kidney diseases

The University of Bristol has secured a £45million deal to advance its groundbreaking gene therapy technology for chronic kidney diseases. The commitment, made by healthcare company Syncona Ltd to Bristol spin-out Purespring Therapeutics, aims to address a global unmet need for renal conditions in one of the largest single investments made to a new UK […]

Technology

Bristol secures £45M to advance gene therapy treatment of chronic kidney diseases

The University of Bristol has secured a £45million deal to advance its groundbreaking gene therapy technology for chronic kidney diseases. The commitment, made by healthcare company Syncona Ltd to Bristol spin-out Purespring Therapeutics, aims to address a global unmet need for renal conditions in one of the largest single investments made to a new UK […]

Technology

Promising results from in vitro combination therapy against COVID-19

Remdesivir, the only approved drug against COVID-19 disease, works by inhibiting an enzyme that prevents the virus from multiplying. In high doses, however, it can cause damage to the liver and the lungs. Human recombinant soluble ACE2 (hrsACE2) is a genetically modified variant of the cell membrane protein angiotensin-converting enzyme 2 (ACE2) that the coronavirus […]

Technology

Promising results from in vitro combination therapy against COVID-19

Remdesivir, the only approved drug against COVID-19 disease, works by inhibiting an enzyme that prevents the virus from multiplying. In high doses, however, it can cause damage to the liver and the lungs. Human recombinant soluble ACE2 (hrsACE2) is a genetically modified variant of the cell membrane protein angiotensin-converting enzyme 2 (ACE2) that the coronavirus […]

Technology

Anti-ageing therapy against metastases | Technology Org

Scientists discovered a genetic factor that determines whether ageing prostate cancer cells either die or become more aggressive. This finding provides important information for personalised therapy of patients. Aging tumour cells stop proliferating. This cell ageing process is called senescence. In cancer therapy, it is deliberately induced with drugs to slow down tumour growth. However, […]

Technology

Cognitive Behavioral Therapy Reduces Insomnia Symptoms Among Young Drinkers

More than half of young adults at risk for alcohol-related harm report symptoms of insomnia. Cognitive-behavioural therapy (CBT) is one of the first-line treatments for insomnia, but it’s never been tested on young adults who are actively drinking. Researchers from the University of Missouri School of Medicine conducted a pilot study to evaluate CBT’s effect on young […]

Technology

Cognitive Behavioral Therapy Reduces Insomnia Symptoms Among Young Drinkers

More than half of young adults at risk for alcohol-related harm report symptoms of insomnia. Cognitive-behavioural therapy (CBT) is one of the first-line treatments for insomnia, but it’s never been tested on young adults who are actively drinking. Researchers from the University of Missouri School of Medicine conducted a pilot study to evaluate CBT’s effect on young […]

Technology

Scientists use gene therapy and a novel light-sensing protein to restore vision in mice

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy. The National Eye Institute, part of the National Institutes of Health, provided a Small Business Innovation Research grant to Nanoscope, LLC for development of MCO1. The company is planning a U.S. clinical […]

Technology

Scientists use gene therapy and a novel light-sensing protein to restore vision in mice

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy. The National Eye Institute, part of the National Institutes of Health, provided a Small Business Innovation Research grant to Nanoscope, LLC for development of MCO1. The company is planning a U.S. clinical […]

Technology

Targeted delivery of anti-inflammatory therapy shows promise in slowing progression of multiple sclerosis

Intranasal administration of an anti-inflammatory drug helped reduce disease progression in a preclinical model of multiple sclerosis, according to recent research out of the University of Alberta. Christopher Power, a professor in the Faculty of Medicine & Dentistry, and Leina Saito, a graduate student on his team, showed that delivering an anti-inflammatory drug to mice helped prevent […]